Allelic exclusion

Allelic exclusion
(Science: cell biology, genetics) The process whereby one or more loci on one of the chromosome sets in a diploid cell is inactivated (or destroyed) so that the locus or loci is (are) not expressed in that cell or a clone founded by it.
For example in mammals one of the x chromosome pairs of females is inactivated early in development (see Lyon hypothesis) so that individual cells express only one allelic form of the product of that locus. Since the choice of chromosome to be inactivated is random, different cells express one or other of the x chromosome products resulting in mosaicism.
The process is also known to occur in immunoglobulin genes so that a clone expresses only one of the two possible allelic forms of immunoglobulin.

Molecules move within the cell or from one cell to another through different strategies. Transport may be in the form of..

Illusions are the perceptions and sensory data obtained from situations in which human error prevents us from seeing the..

It only takes one biological cell to create an organism. A single cell is able to keep itself functional through its 'mi..

This tutorial investigates the genetic diversity in more detail. It also delineates how certain alleles are favored over..

If New Zealand has lots of unique animals, it's also got a whole lot of unique plants. Find out more about some of them,..

Plants, like animals, produce hormones to regulate plant activities, including growth. They need these hormones to respo..

You will also like...