Definition
noun
A type of mutation in which a portion of a genetic material or a chromosome is duplicated or replicated, resulting in multiple copies of that region.
Supplement
Duplication results from an unequal crossing-over between misaligned homologous chromosomes during meiosis. It may involve a replication of a portion of DNA, or of an entire chromosome.
Synonyms:
- gene duplication
- chromosomal duplication
- gene amplification
Compare: deletion mutation.
See also: mutation.