Dictionary > Homogenate

Homogenate

Definition
noun, plural: homogenates
Material that has been homogenized or obtained through homogenization.
Supplement
For example, a liver homogenate is a liver tissue in which its cells have been mechanically disrupted, releasing the organelles and cytoplasm.
The word homogenate was introduced by VR Potter in1941 (J. Biol. Chem 141:775) to refer specifically to suspensions or animal tissues that had been ground in the all-glass “homogenizer”as described by Potter and CA Elvehjem in 1936 (J. Biol. Chem114:495) In the inaugural volume of Methods in Medical Reseach (Vol 1, Van R. Potter, editor-in-chief Yearbook Publishers Chicago:1948) Potter notes that the term had since been used by various investigators to refer to tissue preparations that have been “ground in mortor, with or without sand, or disintegrated in a Waring blendor, or produced by methods not described.” (p. 317) Although these preparations are probably no less appropriately called homogenates, Potter says, in line with the stated goals of Methods in Medical Research, “it seems desirable to promote a nomenclature that is as meaningful as possible, and it is suggested that the method of preparation be specified.” (p.317) The chief significance of the term, he continues, is that “it serves to distinguish the preparation from slices, minces and extracts….the homogenate technique accepts the fact that the cells in the tissue are no longer living and attempts to obtain surviving groups of enzymes word “enzymes” emphasized without loss of in vivo properties.”
Related forms: homogenize (verb), homogenization (noun).


You will also like...

Sugar Homeostasis
Sugar Homeostasis

The blood sugar level is regulated by two hormones. The mechanism behind this type of negative feedback control is descr..

3D rendering of an antibody
Passive and Active Types of Immunity

Lymphocytes are a type of white blood cell capable of producing a specific immune response to unique antigens. In thi..

Cells in different stages of meiosis
Meiosis – The Genetics of Reproduction

Meiosis is a form of cell division that creates gametes. It is comprised of two divisions that in the end, the resulting..

Population Regulation in an Ecosystem
Population Regulation in an Ecosystem

With regard to the population size of a species and what factors may affect them, two factors have been defined. They ar..

Structural depiction of catalase, an enzyme
Protein Activity and Cellular Metabolism

Proteins have a crucial role in various biological activities. Get to know how proteins are able to perform as enzymes, ..

An artistic depiction of Dunkleosteus fish
Fish

The sea was teeming with life. Eventually, through reproduction and continued variation, fish came about. There are over..

Related Articles...

No related articles found

See all Related Topics