Necrosis

Definition
noun, plural: necroses
Premature death of cells in a living tissue or organ caused by the progressive degradative action of enzymes
necrotic, adjective
Of, characterized by, relating to, produced by, or affected with necrosis
Supplement
Necrosis is a term pertaining to the bodily injury characterized by the localized death of cells in a living tissue or organ. Necrosis is different from apoptosis in a way that the former is a premature death of cells or tissues. In apoptosis, the death of a cell occurs naturally and according to the apoptotic signal transduction pathway. In necrosis, the death of a cell is caused not by such pathway but by a mechanism involving the activation of certain receptors resulting in the loss of cell membrane integrity.¹ Factors that lead to necrosis are infection, toxins, and trauma.
Word origin: Ancient Greek nékrōsis (death)
See also:

• apoptosis
• autolysis
• gangrene

Related term(s):

Receptors tumour necrosis factor

Simple necrosis

Infectious pancreatic necrosis virus

Tumour necrosis factor

Caseous necrosis

Coagulation necrosis

Fat necrosis tumour

Fat necrosis

Avascular necrosis

Central necrosis

Colliquative necrosis

Contraction band necrosis

Tumor necrosis factor

Femur head necrosis

Bridging hepatic necrosis

Liquefactive necrosis

Reference(s):

¹Proskuryakov SY, Konoplyannikov AG, Gabai VL; Konoplyannikov; Gabai (2003). “Necrosis: a specific form of programmed cell death?”. Exp. Cell Res. 283(1): 1–16.