Dictionary > Proerythroblast

Proerythroblast

Definition
noun, plural: proerythroblasts
A progenitor cell that arises from the CFU-e, and then develops to become an erythroblast (or normoblast)
Supplement
In vertebrates, including humans, blood is the fluid that circulates in the body to deliver nutrients and oxygen. It is comprised of the plasma and the cellular elements. The cellular elements are the blood cells and the platelets, which are all derived from multipotent stem cells. A hemocytoblast is a multipotent hematopoietic stem cell that gives rise to both lymphoid and myeloid stem cells. The myeloid stem cells are progenitor cells that give rise to erythrocytes, granulocytes, monocytes, and megakaryocytes. The process by which a progenitor cell differentiates into an erythrocyte is referred to as erythropoiesis. A proerythroblast is a cell in the earliest stages of erythropoiesis. It is the precursor cell for erythroblast (or normoblast).
Proerythroblast is sometimes used synonymously with pronormoblast. However, a stricter definition of a proerythroblast would be one that includes both pronormoblast and promegalobast. A pronormoblast is a form of proerythroblast that would undergo normal development whereas a promegaloblast is a form of proerythroblast that undergoes an abnormal development. Thus, a proerythroblast would be an inclusive term for both pronormoblast and promegaloblast.
Proerythroblast is derived from a CFU-e. It becomes a cell that is committed to become an erythrocyte via erythropoiesis. To become one, it develops into an erythroblast (or normoblast), which then develops into a reticulocyte, and then finally into an erythrocyte.
Synonym(s):

  • pronormoblast
  • rubriblast

See also:

  • blood cell
  • erythropoiesis
  • normoblast


  • You will also like...

    Buttress roots
    Roots

    This study guide tackles plant roots in greater detail. It delves into the development of plant roots, the root structur..

    Homeostatic Mechanisms and Cellular Communication
    Homeostatic Mechanisms and Cellular Communication

    Homeostasis is the relatively stable conditions of the internal environment that result from compensatory regulatory res..

    Freshwater Ecology
    Freshwater Ecology

    Freshwater ecology focuses on the relations of aquatic organisms to their freshwater habitats. There are two forms of co..

    A chart depicting Mendel's Law of Dominance
    Mendel’s Law & Mendelian Genetics

    One of Mendel’s law of inheritance is the “law of dominance”. Read this tutorial to know more about this form of i..

    DNA molecule
    Genetic Control – On and Off Genes

    Genes are the blueprint of our bodies, a blueprint that creates a variety of proteins essential to any organism's surviv..

    Crossing Over and Genetic Diversity
    Inheritance and Probability

    Gregor Mendel, an Austrian monk, is most famous in this field for his study of the phenotype of pea plants, including ..

    Related Articles...

    No related articles found

    See all Related Topics